A 5-year sensitivity analysis of a recent trial showed improved efficacy outcomes and toxicity profiles for patients receiving a new adjuvant therapy for HER2-positive breast cancer. READ MORE

Conferences

Researchers from Denmark followed a group of women diagnosed with breast cancer to compare breast conserving therapy with mastectomy. 

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Investigators examined potential biomarkers for the breast cancer gene GATA3 to see if any could be associated with patients’ survival.

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Researchers evaluated bone health surveillance patterns, bone density outcomes, and fracture risk after salpingo-oophorectomy.

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Presenters called for new ways to evaluate the success of novel agents for the treatment of breast cancer. 

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News

A recent phase III trial demonstrated that initial therapy with an immuno-agent improves PFS in patients with HR+, HER2- breast cancer.

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A recent study found that 29% of breast cancer clinical trials are not comprised of control arms consistent with the current standard of care.

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A recent survey found that 90% of patients treated with radiation therapy for breast cancer found their experiences to be less “scary” than anticipated.

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Breast cancer surgeons play a big role in deciding whether women with early-stage breast cancer undergo a controversial operation to have both breasts removed, even when cancer is found in only one.

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Research in Review

Patients with human epidermal growth factor 2 (HER2)-positive breast cancer who undergo induction chemotherapy are likely to convert to HER2-negative disease if residual disease occurs, prompting further systemic therapy.

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Patients with human epidermal growth factor receptor 2-positive breast cancer benefit from an estimated 7 additional months of survival if treated with trastuzumab emtansine rather than the physician’s choice of therapy.

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A radiation schedule half the standard course is as safe and effective for patients with breast cancer following a mastectomy.

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MRI results after percutaneous biopsy for ductal carcinoma in situ often overestimate the extent of breast cancer, resulting in unnecessary mastectomies.

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