Testing for mismatch repair deficiency remains underused among adults with colorectal cancer, despite the existence of well-established guidelines aimed at high-risk populations. READ MORE
Quality metrics may not lead to better overall survival in patients with surgically resected stage 3 colon cancer.
For patients with complications after colorectal surgery, being readmitted to the same medical center and being cared for by the surgeon who performed the operation may increase the likelihood of survival.
Research in Review
Short-course preoperative radiotherapy combined with delayed surgery reduces the adverse effects of rectal cancer surgery while maintaining its efficiency, according to a study published in The Lancet (published online February 9, 2017; doi: 10.1016/S1470-2045(17)30086-4).
Chemotherapy may be overused among young and middle-aged patients with colon cancer.
The addition of BRAF-inhibitor vemurafenib to irinotecan and cetuximab chemotherapy treatment improves progression-free survival.
Nivolumab has shown disease control in pretreated patients with DNA mismatch repair deficient/microsatellite instability high metastatic colorectal cancer.