By Marilynn Larkin

NEW YORK (Reuters Health) – Adding external beam radiation therapy (EBRT) to radioactive iodine (RAI) leads to good disease control in locally advanced, differentiated thyroid cancer, especially for patients with tracheal or esophageal invasion who received aggressive surgical resection, researchers say

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News

Patients with a non-thyroid cancer who experience hypothyroidism during cancer treatment with a TKI benefit from significantly increased survival compared with those who have normal thyroid function.

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By Marilynn Larkin

NEW YORK (Reuters Health) – Thyroidectomy rates in Medicare beneficiaries vary 6.2-fold across the United States, suggesting widely divergent local beliefs and practice patterns about how to manage thyroid cancer, researchers say.

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Approximately 66% of patients with medullary thyroid carcinoma do not receive a complete thyroidectomy or central neck lymph-node dissection, despite recommendations in the American Thyroid Guidelines suggesting combining the two procedures.

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A US study looking at the natural history and growth parameters of small, low-risk papillary thyroid cancers supports active surveillance as a management option.

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Research in Review

PD-L1 expression may be a biomarker of local failure in human papillomavirus (HPV)-negative head and neck squamous cell carcinoma following radiotherapy.

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Patients aged 80 years or older with early-stage esophageal cancer who received treatment had an increased 5-year overall survival compared with those who received no treatment or observation alone.

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A combination therapy for patients with newly diagnosed glioblastoma maintains improvement in overall survival (OS) after 5 years, according to recently published results of a phase III trial.

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Response to a single dose of neoadjuvant chemotherapy indicates the optimal treatment course for patients with laryngeal cancer, according to a study published in JAMA Otolaryngology (published online February 2, 2017; doi:10.1001/jamaoto.2016.3669).

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